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Sedation

208 - Incident of Postoperative Adverse Effects Following IV General Anesthesia

Friday, May 22, 2026
4:40 PM - 4:55 PM PST
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    Presenting Author(s)

  • John Yuan, DDS (he/him/his)

    Pediatric Dental Resident
    University of Texas Health Science Center-Houston
    University of Texas Health Science Center Houston
    Houston, Texas, United States

    • Co-Author(s)

  • Brett T. Chiquet, DDS, PhD (he/him/his)

    Professor and Chair, Department of Pediatric and Community Dentistry
    UTHealth
    University at Buffalo School of Dental Medicine
    Buffalo, New York, United States

  • Brandon Key, DDS

    Dentist Anesthesiologist
    UTHealth Houston | School of Dentistry
    UTHealth Houston | School of Dentistry

  • Lydia L. Brett, DMD, MS

    PGY-2 Pediatric Resdient
    UTHealth Houston | School of Dentistry
    UTHealth Houston School of Dentistry
    Houston, Texas, United States

    • Program Director(s)

  • AC

    Antonio D. Cardenas, DDS, MS

    Pediatric Dentistry Postgraduate Program Director
    UTHealth
    Houston, Texas, United States

Abstract:

Purpose: To compare the postoperative recovery periods of enteral moderate sedation and parenteral general anesthesia in pediatric dentistry




Methods: Parents of pediatric dental patients aged 2-18 years (ASA I-II) who received dental treatment under parenteral GA, consisting of intramuscular induction followed by total intravenous anesthesia, were recruited to complete a postoperative survey assessing recovery at 1, 4, 8, and 24 hours post-discharge. This survey was previously validated evaluating postoperative recovery following enteral moderate sedation. Responses from the general anesthesia cohort were compared with the existing enteral moderate sedation dataset. Fisher’s exact test, chi-square analysis, and generalized linear models utilized, with P< .05 considered statistically significant.




Results: Parents of 10 patients undergoing IV-anesthesia completed the postoperative survey, compared with 100 responses from the enteral moderate sedation dataset. One hour post-discharge, the IV-anesthesia group demonstrated a higher incidence of transient neurologic/functional effects, including dizziness (40%, P=.003), trouble concentrating (40%, P=.012), and difficulty eating or drinking (30%, P=.048). These differences were not present at the 4-hour assessment. No significant differences were observed in alertness (P=.35), behavior (P=.79), or activity (P=.62).




Conclusion: Parenteral general anesthesia in pediatric dentistry was associated with a higher incidence of transient neurologic effects during the first postoperative hour compared with enteral moderate sedation. These effects were self-limited/resolved as recovery progressed. Despite the small sample size, findings support the safety of in-office parenteral general anesthesia, with preservation of alertness, behavior, and activity with no serious adverse events observed.

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