167 - Molar–Incisor Hypomineralization and Short Root Anomaly in U.S. Children

Abstract:

Purpose: To evaluate the association between Molar-Incisor Hypomineralization (MIH) and co-existing developmental dental anomalies (DDA). Also, to determine if ethnic disparities exist between controls and children with MIH/DDA.

Methods: Children between the ages of 6-14 years were examined for the presence of MIH and co-existing DDA by calibrated examiners using standardized diagnostic criteria. Demographic data were obtained by structured questionnaires. DDAs were identified through clinical and radiographic assessment. Statistical analyses included descriptive statistics, Chi-square and Fisher's exact tests, and logistic regression.

Results: A total of 156 children (MIH n=83, controls n=73 subjects) were enrolled. Mean age was 9.43 ± 1.97 in the case group and 8.54 ± 1.77 years in the control group. The majority of the subjects in both groups were born in the United States and were Hispanic/Latino, with no differences in gender, birthplace, or ethnicity (P>.05). The prevalence of any DDA was significantly higher in the MIH than the control group (39.5% vs 13.7%, P < .001). Short root anomaly (p=0.004) and microdontia (p=0.036) were significantly higher in MIH than non-MIH children. Multivariable logistic regression analysis showed that MIH remained independently associated with the presence of any DDA after adjusting for country, gender, and ethnicity (aOR=4.52; 95% CI: 1.97–10.33; P < .001).

Conclusions: Children with MIH were 4.5 times more likely to exhibit concurrent DDA than unaffected peers, which denotes an additional burden to this population.

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